Biohack-it

I finally sat down with the incredible Dr. Natalia Spierings, and she is exactly the kind of pattern-interrupt this industry needs. Natalia isn’t just a UK-trained consultant dermatologist and surgeon—she is also a professional IFBB bodybuilder. Today, we are cutting through the multi-billion dollar marketing hype to get to the "no bullshit" truth about your skin and your body.

In this episode, Natalia exposes why most skincare products are essentially useless and why she believes Vaseline is closer to magic than any luxury serum. We dive deep into the science of Tretinoin, the dangers of long-term fillers (and the "alien" looks they can create), and why fat transfer might be a better surgical alternative for under-eye rejuvenation.

We also discuss the bodybuilding mindset: why most women fail to change their body composition despite lifting weights, and the power of DEXA scanning to keep you accountable. If you’re tired of "hope in a bottle" and want a straightforward, evidence-based approach to longevity and anti-aging, this masterclass is for you.

Connect with Dr. Natalia Spierings:
Instagram: @drnataliaspierings

Sponsors:
Vibrant Wellness: Get the Hormone Zumra test to understand your body’s unique needs. Visit http://vibrant-wellness.com/imanhasan

Chapters:
00:00:00 – Intro
00:01:37 – The Bodybuilding Pivot: From Cycling Accident to the UK Arnold
00:03:55 – The Bodybuilding Mindset in Medicine: Stick to the Basics
00:05:00 – Tretinoin: The Real Gold Standard for Anti-Aging
00:06:48 – The Biggest Skincare Lie: Why Drinking Water Doesn’t Hydrate Skin
00:09:28 – The Danger of Injectables: FDA Approval vs. Efficacy
00:11:00 – Under-Eye Tragedies: Why Fillers Can Block Your Lymphatic System
00:13:38 – Fat Transfer vs. Fillers: A Surgeon’s Take on Volume Loss
00:16:50 – Skincare Scams: Why Peptides and Exosomes are Marketing Gimmicks
00:23:13 – Debunking "Clean" Scams: The Truth About Hydroquinone and Minoxidil
00:25:20 – HRT and Skin: Why Doctors Should Stay in Their Lane
00:30:05 – Botox Myths and the Rise of "Alien" Aesthetic Faces
00:33:32 – Body Composition: Why You’re Not Gaining Muscle
00:35:36 – Knowledge is Power: The Role of DEXA Scanning in Longevity

I have followed Dr. Natalie Crawford for years, and having her on the show is a true full-circle moment for me. As a board-certified reproductive endocrinologist, Natalie is a beacon of knowledge for anyone navigating a fertility journey. In this episode, she gets incredibly raw about her own struggle with infertility and how being gaslit by the medical system led her to discover the "big dirty secret" of reproductive health: inflammation.

We dive deep into the science of ovarian aging and why your "biological clock" is about more than just your age. Natalie explains how mitochondrial health and insulin resistance are the real drivers of egg quality and how you can proactively lower your inflammatory burden through sleep, nutrition, and nervous system regulation. Whether you are considering IVF, egg freezing, or just want to understand your hormones better, this masterclass in preventive care is for you.

In this episode, we discuss:
The connection between chronic stress, cortisol, and fertility loss.
Why building skeletal muscle is the key to fighting insulin resistance.
The truth about forever chemicals (PFCs) in your kitchen and water.
The latest research on Rapamycin and PRP for ovarian longevity.
A step-by-step guide to cycle tracking and identifying ovulation signs.

I have been trying to get Dr. Amy Shah on Biohack-it for 18 months, and we finally made it happen while filming in Riyadh, Saudi Arabia. As two South Asian women, we dive straight into a conversation that hits close to home: why our race is built so petite yet remains at a significantly higher risk for type 2 diabetes, Alzheimer’s, and heart disease than other populations.In this episode, Dr. Amy Shah breaks down the fascinating science of "thrifty genes"—the biological survival mechanism from ancestral famines that makes our bodies hold onto sugar differently. We discuss the "skinny-fat" phenomenon and how modern lifestyle choices, like processed seed oils and a lack of protein, are creating a metabolic crisis. Dr. Shah shares her proprietary 30-3-3 rule for gut health and her signature "cortisol reset" to help you regulate your nervous system and reclaim your energy.Sponsors: Vibrant Wellness: Get the Hormone Zumra test to understand your body’s unique needs. Visit http://vibrant-wellness.com/imanhasan

I’m getting really uncomfortable today. My team told me it was time for "More of Me," so I’m sitting down to answer the questions you sent in on Instagram—nothing is off the table. From my divorce and the move to Dubai to the heartbreaking reason I pivoted my entire career into health and wellness after losing my mother to terminal cancer, this is the most personal I’ve ever been.

We’re diving deep into the biohacking protocols I use to stay high-performing while running two companies. I’m sharing my exact 2026 peptide stack (including BPC-157 and GHK-Cu), the truth about cellular health, and the one supplement I will never live without. We also discuss my life-changing Ayahuasca journey in Mexico and how it helped me find peace with my father's passing. If you’ve ever felt like a victim of your circumstances, I want to show you how to become the hero of your own story through curiosity, accountability, and the right nervous system regulation.

In this episode, we cover:
My move to the Middle East and the future of the UAE.
The "Nesting" method for co-parenting after divorce.
How to spot a "fraud" in the wellness industry.
The science of mitochondria, cortisol regulation, and box breathing.

Sponsors:
Vibrant Wellness: Get the Hormone Zumra test to understand your body’s unique needs. Visit http://vibrant-wellness.com/imanhasan

In this episode, I sit down with a man who was instrumental in my own healing journey: the "medical shaman" himself, Dr. Ivan Rusilko. We’re diving deep into the hot topic taking over the US right now—peptides. But we aren't just talking about the surface-level trends; we're breaking down the critical difference between medical-grade and "research" peptides, and why where you source your "key" to cellular health matters more than you think.
I share the vulnerable story of my own nervous system breakdown and why I chose to ignore the recommendation for SSRIs, opting instead for a four-week protocol with Ivan that didn't just bring me back to life—it made me feel better than my original self. We also discuss his incredible work reversing "incurable" conditions, including a 96% drop in cancer markers for a Stage 4 patient and restoring the quality of life for an 85-year-old battling Parkinson’s.
From the neuroplasticity of ketamine and the "miracle grow" properties of Cerebrolysin to the spiritual "Law of Amplification," this episode is an masterclass in living an extravagant, healthy, and high-frequency life.

Sponsors:
Vibrant Wellness: Get the Hormone Zumra test to understand your body’s unique needs. Visit [vibrant-wellness.com/biohack-it].

Chapters:

[00:00] – Intro
[01:30] – The Diagnostic Puzzle: Treating the Person, Not Just the Lab
[02:45] – Case Study: The 60-Year-Old "Patient Zero"
[04:00] – The Three Tiers of Stress: Emotional, Biological, and Mental
[06:30] – Core Memories: Lessons from a Pennsylvania Hunting Trip
[10:30] – Walking the Walk: Why Your Doctor Should Look Like a Hero
[12:45] – Peptides Explained: Medical Grade vs. Research Grade
[15:50] – My Personal Crisis: Choosing Peptides Over SSRIs
[18:00] – The Truth About Ketamine: Stints vs. Perpetuity
[21:00] – Reversing Parkinson’s: Lee’s Story of Getting His Life Back
[24:00] – The EBV vs. HIV Shock: The Hidden Drain of Chronic Viruses
[26:00] – The Science of Sleep: Alpha, Delta, and REM Cycles
[28:30] – Deep Dive into Peptides: BPC-157, Cerebrolysin, and Dihexa
[34:30] – Healing Stage 4 Breast Cancer: The Polyphenol "Hat Trick"
[39:30] – The Law of Amplification: Living Life in Full Spectrum
[44:00] – The Energetics of Sex: Oxytocin, Pair Bonding, and Protection
[48:00] – The Audacity to Live: Final Thoughts on Authenticity