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This Week in Virology

Vincent Racaniello
This Week in Virology
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  • This Week in Virology

    TWiV 1326: Clinical update with Dr. Daniel Griffin

    30/05/2026 | 38 min
    In his weekly clinical update, Daniel Griffin and Vincent Racaniello comment on incidences of locally transmitted malaria in the US, mpox diagnostics, the latest developments surrounding hantavirus infections, and the Ebola outbreak in the Congo and Uganda including vaccine candidates before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the measles outbreak in Texas in 2025, how to access and pay for Paxlovid, where to go for answers about long COVID-19, casual association of auto-antibodies and COVID complications and contacting your federal government representative to stop the assault on science and biomedical research.
    Subscribe (free): Apple Podcasts, RSS, email
    Become a patron of TWiV!
    Links for this episode
    CDC Operational Guidance for Investigating Locally Acquired Mosquito-Transmitted Malaria — United States, 2026 (CDC: MMWR)
    Performance of five mpox antigen-based rapid diagnostic tests tested on lesion swabs from patients with suspected mpox from the Kinshasa province of DR Congo: a diagnostic accuracy study (LANCET: Infectious Diseases)
    Hantavirusdashboard (Hantavirus.up)
    Andes Hantavirus Outbreak on a Cruise Ship, 2026 (NEJM)
    “Super-Spreaders” and Person-to-Person Transmission of Andes Virus in Argentina (NEJM)
    Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 (CDC: Emerging Infectious Diseases)
    Hantavirus on board with Prof. VincentRacaniello (microbeTV)
    Ebola dashboard (ebola.fyi)
    Epidemic of Ebola Disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern (WHO)
    WHO ramps up support to the Democratic Republic of the Congo’s Ebola outbreak response (WHO: Democratic Republic of Congo)
    WHO chief says fast-moving Ebola epidemic is outpacing response efforts (Reuters)
    US CDC seeks staff for Ebola screening as outbreak response expands (Reuters)
    Trump Administration to Send Americans Exposed to Ebola to Kenya (NY Times)
    Single Immunization With a Monovalent Vesicular Stomatitis Virus–Based Vaccine Protects Nonhuman Primates Against Heterologous Challenge With Bundibugyo ebolavirus (JID)
    Vesicular Stomatitis Virus-Based Vaccines Protect Nonhuman Primates against Bundibugyo ebolavirus (PLoS Neglected Tropical Diseases)
    Vaccine experts debate options to combat outbreak of unusual Ebola strain (Science)
    NIAID Establishes Centers for Research in Emerging Infectious Diseases (NIAID.NIH)
    Inside the Race to Develop a Test for the Rare Andes Hantavirus (Wired)
    NIH terminates network aimed at stopping pandemics before they start (Science)
    These Researchers Would Be in Africa Fighting Ebola—but Trump Cut Their Funding (Wired)
    Wastewater for measles (WasterWater Scan)
    Measles cases and outbreaks (CDC Rubeola)
    Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health)
    Utah measles outbreak response (Utah Department of Health and Human Services)
    Utah Measles Dashboard (Utah Department of Health and Human Services)
    Tracking Measles Cases in the U.S. (Johns Hopkins)
    Measles vaccine recommendations from NYP (jpg)
    Weekly measles and rubella monitoring (Government of Canada)
    Measles (WHO)
    Get the FACTS about measles (NY State Department of Health)
    Measles (CDC Measles (Rubeola))
    Measles vaccine (CDC Measles (Rubeola))
    Presumptive evidence of measles immunity (CDC)
    Contraindications and precautions to measles vaccination (CDC)
    Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
    Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
    Deaths following vaccination: what does the evidence show (Vaccine)
    Characteristics of Patients Hospitalized with Measles During an Outbreak — West Texas, January–March 2025 (CDC:MMWR)
    Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
    USrespiratory virus activity (CDC Respiratory Illnesses)
    Respiratory virus activity levels (CDC Respiratory Illnesses)
    Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
    WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
    FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
    Weekly surveillance report: cliff notes (CDC FluView)
    OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
    RSV: Waste water scan for 11 pathogens (WastewaterSCan)
    Respiratory Diseases (Yale School of Public Health)
    USrespiratory virus activity (CDC Respiratory Illnesses)
    RSV-Network (CDC Respiratory Syncytial virus Infection)
    Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
    Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
    Respiratory Diseases (Yale School of Public Health)
    Waste water scan for 11 pathogens (WastewaterSCan)
    COVID-19 deaths (CDC)
    Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
    COVID-19 national and regional trends (CDC)
    COVID-19 variant tracker (CDC)
    SARS-CoV-2 genomes galore (Nextstrain)
    US FDA advisers to weigh updating 2026-27 COVID vaccines for XFG variant (Reuters)
    Where to get pemgarda (Pemgarda)
    EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
    Infusion center (Prime Fusions)
    CDC Quarantine guidelines (CDC)
    NIH COVID-19 treatment guidelines (NIH)
    Drug interaction checker (University of Liverpool)
    Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
    UnderstandingCoverageOptions (PAXCESS)
    Infectious Disease Society guidelines for treatment and management (ID Society)
    Molnupiravir safety and efficacy (JMV)
    Convalescent plasma recommendation for immunocompromised (ID Society)
    What to do when sick with a respiratory virus (CDC)
    Managing healthcare staffing shortages (CDC)
    Anticoagulation guidelines (hematology.org)
    Daniel Griffin’s evidence based medical practices for long COVID (OFID)
    Long COVID hotline (Columbia : Columbia University Irving Medical Center)
    The answers: Long COVID
    A causallink between autoantibodies and neurological symptoms in long COVID (Cell)
    Reaching out to US house representative
    Dr. Griffin’s COVID treatment summary (pdf)
    Timestamps by Jolene Ramsey. Thanks!
    Intro music is by Ronald Jenkees
    Send your questions for Dr. Griffin to [email protected]
    Content in this podcast should not be construed as medical advice.
  • This Week in Virology

    TWiV 1325: Sticky flu with Hannah Rowe

    24/05/2026 | 57 min
    Vincent travels to Oregon State University in Corvallis to meet up with Hannah Rowe to talk about her career and her work demonstrating how the interaction of influenza A virus and Streptococcus pneumonia influences transmission.
    Hosts: Vincent Racaniello
    Guest: Hannah Rowe
    Subscribe (free): Apple Podcasts, RSS, email
    Become a patron of TWiV!
    Links for this episode
    Support science education at MicrobeTV
    Positions in Rosenfeld Lab (email)
    Respiratory bacteria stabilize influenza A virus (mSystems)
    S. pneumoniae and influenza A virus binding (mSphere)
    Bacterial alteration of redox stressors and stability of influenza A virus (mSphere)
    Timestamps by Jolene Ramsey. Thanks!
    Intro music is by Ronald Jenkees
    Send your virology questions and comments to [email protected]
    Content in this podcast should not be construed as medical advice.
  • This Week in Virology

    TWiV 1324: Clinical update with Dr. Daniel Griffin

    23/05/2026 | 45 min
    In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss withdrawal of the ACIP charter published in April 2026, the first council meeting on antibiotic resistant bacteria, the latest developments surrounding hantavirus infections, and the Ebola outbreak in the Congo and Uganda before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, transmission of SARS-CoV-2 through the air including ventilation systems, how to access and pay for Paxlovid, where to go for answers about long COVID-19, early use of antiviral drugs for COVID-19 patients and contacting your federal government representative to stop the assault on science and biomedical research.
    Subscribe (free): Apple Podcasts, RSS, email
    Become a patron of TWiV!
    Links for this episode
    US health department withdraws vaccine advisory panel charter (Reuters)
    Meeting of the Presidential Advisory Council on Combating Antibiotic-Resistant
    Bacteria (Federal Register)
    Andes Hantavirus Outbreak on a Cruise Ship, 2026 (NEJM)
    “Super-Spreaders” and Person-to-Person Transmission of Andes Virus in Argentina (NEJM)
    Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 (CDC: Emerging Infectious Diseases)
    Hantavirus on board with Prof. VincentRacaniello (microbeTV)
    Hantavirus Doesn’t Spread Easily, but Officials May Be Downplaying Risks (NY Times)
    Cross-binding antibodies capable of neutralising diverse hantaviruses are produced in response to Puumala virus infection (eBioMedicine)
    Hantavirus dashboard (Hantavirus.live)
    Visualizing the hantavirus cruise outbreak in maps and charts (CNN)
    Epidemic of Ebola Disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern (WHO)
    Ebola outbreak response intensifies in DRC and Uganda as cases mount (DG: Alerts)
    WHO ramps up support to the Democratic Republic of the Congo’s Ebola outbreak response (WHO: Democratic Republic of Congo)
    Vaccine experts debate options to combat outbreak of unusual Ebola strain (Science)
    US promises to fund clinic established to treat Ebola (X-USForeignAssist)
    U.S.-Bound Flight Diverted to Canada Because of Ebola Restrictions (NY Times)
    Wastewater for measles (WasterWater Scan)
    Measles cases and outbreaks (CDC Rubeola)
    Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health)
    Utah measles outbreak response (Utah Department of Health and Human Services)
    UtahMeasles Dashboard (Utah Department of Health and Human Services)
    Tracking Measles Cases in the U.S. (Johns Hopkins)
    Measles vaccine recommendations from NYP (jpg)
    Weekly measles and rubella monitoring (Government of Canada)
    Measles (WHO)
    Get the FACTS about measles (NY State Department of Health)
    Measles(CDC Measles (Rubeola))
    Measles vaccine (CDC Measles (Rubeola))
    Presumptive evidence of measles immunity (CDC)
    Contraindications and precautions to measles vaccination (CDC)
    Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
    Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
    Deaths following vaccination: what does the evidence show (Vaccine)
    Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
    USrespiratory virus activity (CDC Respiratory Illnesses)
    Respiratory virus activity levels (CDC Respiratory Illnesses)
    Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
    WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
    FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
    Weekly surveillance report: cliff notes (CDC FluView)
    OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza)
    RSV: Waste water scan for 11 pathogens (WastewaterSCan)
    Respiratory Diseases (Yale School of Public Health)
    US respiratory virus activity (CDC Respiratory Illnesses)
    RSV-Network (CDC Respiratory Syncytial virus Infection)
    Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
    Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
    Respiratory Diseases (Yale School of Public Health)
    Maternal RSV Vaccination, Infant Nirsevimab, or Both: Interim Analysis of a Randomized Trial (Pediatrics)
    Waste water scan for 11 pathogens (WastewaterSCan)
    COVID-19 deaths (CDC)
    Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
    COVID-19 national and regional trends (CDC)
    COVID-19 variant tracker (CDC)
    SARS-CoV-2 genomes galore (Nextstrain)
    Potential airborne transmission of SARS-COV-2 through bathroom ventilation ducts associated with an outbreak in a residential building in Santander, Spain, 2020 (PLoS One)
    Where to get pemgarda (Pemgarda)
    EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
    Infusion center (Prime Fusions)
    Recent COVID-19 Vaccination and Risk of SARS-CoV-2 Transmission (JAMA Network OPEN)
    CDC Quarantine guidelines (CDC)
    NIH COVID-19 treatment guidelines (NIH)
    Drug interaction checker (University of Liverpool)
    Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
    UnderstandingCoverageOptions (PAXCESS)
    Infectious Disease Society guidelines for treatment and management (ID Society)
    Molnupiravir safety and efficacy (JMV)
    Convalescent plasma recommendation for immunocompromised (ID Society)
    What to do when sick with a respiratory virus (CDC)
    Managing healthcare staffing shortages (CDC)
    Anticoagulation guidelines (hematology.org)
    Daniel Griffin’s evidence based medical practices for long COVID (OFID)
    Long COVID hotline (Columbia : Columbia University Irving Medical Center)
    The answers: Long COVID
    Early antiviral use may lower risk of long COVID in mildly ill patients, aid recovery from infection (CIDRAP)
    Early-Phase Oral Antiviral Use and Post–COVID-19 Condition in Outpatients (JAMA Network OPEN)
    Impact of Early Oral Antiviral Use for Outpatients With COVID-19 on Healthcare Utilization and Recovery (ANCHOR-02) (International Journal of Infectious Diseases) Reaching out to US house representative
    Letters read on TWiV 1324
    Dr. Griffin’s COVID treatment summary (pdf)
    Timestamps by Jolene Ramsey. Thanks!
    Intro music is by Ronald Jenkees
    Send your questions for Dr. Griffin to [email protected]
    Content in this podcast should not be construed as medical advice.
  • This Week in Virology

    TWiV 1323: One influenza infection, two patients

    17/05/2026 | 1 h 48 min
    TWiV explains mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines, and how toll-like receptor 7 alters the maternal immune landscape during influenza A infection to increase maternal and fetal morbidity,
    Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler
    Subscribe (free): Apple Podcasts, RSS, email
    Become a patron of TWiV!
    Links for this episode
    Support science education at MicrobeTV
    Positions in Rosenfeld Lab (email)
    RFK Jr. driving vast inquiry into vaccines (NY Times)
    Indiana plant biologist locked out of lab by school (Science)
    Trump cuts CDC role in PEPFAR (Science)
    Ralph Baric retires (The Assembly)
    Baric to fight NIH funding ban (Science)
    Ebola outbreak in DRC (npr)
    Persistence of Andes virus RNA in human semen (Viruses)
    mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines (Cell Rep)
    Science will break your heart (TWiV 920)
    TLR7 and maternal and fetal morbidity during influenza (Sci Adv)
    Letters read  on TWiV 1323
    Timestamps by Jolene Ramsey. Thanks!
    Weekly Picks
    Kathy – Bloomberg Connects app and What’s in Bloom  Peony Season 2026 Bloom Tracker
    Rich – Medpage Today: What you need to know about hantavirus
    Vincent – Apollo 11 Almost Never Left the Moon
    Intro music is by Ronald Jenkees
    Send your virology questions and comments to [email protected]
    Content in this podcast should not be construed as medical advice.
  • This Week in Virology

    TWiV 1322: Clinical update with Dr. Daniel Griffin - Hantavirus special

    16/05/2026 | 53 min
    In his weekly clinical update, Daniel Griffin and Vincent Racaniello reviewed the latest developments surrounding the hantavirus outbreak, including new interim guidance from the Centers for Disease Control and Prevention for the management of infectious cases, whether the CDC may be downplaying the significance of the outbreak because of public backlash following the COVID-19 pandemic, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, benefit of maternal vaccination against RSV for infants, efficacy and safety of a mRNA influenza vaccine  how to access and pay for Paxlovid, where to go for answers about long COVID-19, multisystem inflammatory syndrome in children and contacting your federal government representative to stop the assault on science and biomedical research.
    Subscribe (free): Apple Podcasts, RSS, email
    Become a patron of TWiV!
    Links for this episode
    Interim Guidance for Public Health Assessment and Management of People with Potential Exposure to Andes Virus Outbreak (CDC)
    Hantavirus in humans: a review of clinical aspects and management (LANCET: Infectious Diseases)
    “Super-Spreaders” and Person-to-Person Transmission of Andes Virus in Argentina (NEJM)
    Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 (CDC: Emerging Infectious Diseases)
    Hantavirus on board with Prof. Vincent Racaniello (microbeTV)
    Transcript – Updateon CDC’s Hantavirus Response 5/13/2026 (CDC)
    CDC Is Walking a Tightrope With Its Response to Hantavirus (Wall Street Journal)
    What Happened on the Hantavirus Cruise, According to a Doctor On Board (The Atlantic)
    Andes hantavirus outbreak on a cruise ship – an ESCMID Emerging Infections Subcommittee (EIS) rapid assessment (CMI: Clinical Microbiology and Infection)
    Wastewater for measles (WasterWater Scan)
    Measles cases and outbreaks (CDC Rubeola)
    Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health)
    Utah measles outbreak response (Utah Department of Health and Human Services)
    Utah Measles Dashboard (Utah Department of Health and Human Services)
    Tracking Measles Cases in the U.S. (Johns Hopkins)
    Measles vaccine recommendations from NYP (jpg)
    Weekly measles and rubella monitoring (Government of Canada)
    Measles (WHO)
    Get the FACTS about measles (NY State Department of Health)
    Measles (CDC Measles (Rubeola))
    Measles vaccine (CDC Measles (Rubeola))
    Presumptive evidence of measles immunity (CDC)
    Contraindications and precautions to measles vaccination (CDC)
    Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
    Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
    Deaths following vaccination: what does the evidence show (Vaccine)
    Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
    USrespiratory virus activity (CDC Respiratory Illnesses)
    Respiratory virus activity levels (CDC Respiratory Illnesses)
    Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
    WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
    FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
    Weekly surveillance report: cliff notes (CDC FluView)
    Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults (NEJM)
    OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
    RSV: Waste water scan for 11 pathogens (WastewaterSCan)
    Respiratory Diseases (Yale School of Public Health)
    US respiratory virus activity (CDC Respiratory Illnesses)
    RSV-Network (CDC Respiratory Syncytial virus Infection)
    Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
    Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
    Respiratory Diseases (Yale School of Public Health)
    Maternal RSV Vaccination, Infant Nirsevimab, or Both: Interim Analysis of a Randomized Trial (Pediatrics)
    Waste water scan for 11 pathogens (WastewaterSCan)
    COVID-19 deaths (CDC)
    Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
    COVID-19 national and regional trends (CDC)
    COVID-19 variant tracker (CDC)
    SARS-CoV-2 genomes galore (Nextstrain)
    Life lost due to the COVID-19 pandemic: A model-based cohort analysis of mortality displacement in the registered population of England (PLoS One)
    Where to get pemgarda (Pemgarda)
    EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
    Infusion center (Prime Fusions)
    Ensitrelvir for Covid-19 Postexposure Prophylaxis in Household Contacts (NEJM)
    CDC Quarantine guidelines (CDC)
    NIH COVID-19 treatment guidelines (NIH)
    Drug interaction checker (University of Liverpool)
    Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
    Understanding Coverage Options (PAXCESS)
    Infectious Disease Society guidelines for treatment and management (ID Society)
    Molnupiravir safety and efficacy (JMV)
    Convalescent plasma recommendation for immunocompromised (ID Society)
    What to do when sick with a respiratory virus (CDC)
    Managing healthcare staffing shortages (CDC)
    Anticoagulation guidelines (hematology.org)
    Daniel Griffin’s evidence based medical practices for long COVID (OFID)
    Long COVID hotline (Columbia : Columbia University Irving Medical Center)
    The answers: Long COVID
    Reaching out to US house representative
    Letters read on TWiV 1322
    Dr. Griffin’s COVID treatment summary (pdf)
    Timestamps by Jolene Ramsey. Thanks!
    Intro music is by Ronald Jenkees
    Send your questions for Dr. Griffin to [email protected]
    Content in this podcast should not be construed as medical advice.
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