Masters of Scale

In this encore episode of Rapid Response, we revisit a scientific breakthrough that set the internet ablaze: The ‘de-extinction’ of the dire wolf. While many celebrated Colossal Biosciences’ announcement, the experiment also sparked controversy throughout the scientific community — namely the ethics of birthing and re-wilding extinct animals, and whether Colossal’s dire wolf puppies are the real thing. Colossal’s co-founder and CEO Ben Lamm joined host Bob Safian to take us inside the dire wolf journey, revealing how the startup attracted a roster of celebrity investors, and what the company’s technology means for not only conservation and biodiversity, but potentially the future of human health. Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

After serving as Chief Legal Officer and then CFO at Salesforce, Amy Weaver sought a new challenge. She is now CEO of Direct Relief, which she tells host Jeff Berman is "the largest, most efficient, most effective, and most impactful global humanitarian group that you may never have heard of.” Weaver reveals scale lessons from Salesforce and how she's now applying them to amplify Direct Relief's vital work.Learn more about Direct Relief: directrelief.orgSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/newsletter/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This year delivered whiplash: geopolitics, tariffs, and technology all shifting at once. And heading into 2026, the disruption isn’t easing up. In this special episode, host Bob Safian distills five hard-won lessons from Rapid Response this year on how to lead when the ground won’t stop moving. You’ll hear standout moments from Brian Chesky, Clara Shih, Marc Lore, José Andrés, and more, with practical takeaways for turning uncertainty into advantage.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

With over two billion in annual revenue and nearly 7,000 employees, Gensler has cemented itself as a global icon in architecture and design. Host Jeff Berman talks with co-CEO Elizabeth Brink and global co-chair Andy Cohen about why the company has doubled down on a collaborative leadership model, the ways AI is disrupting their industry, and how they’re designing for the future of work. Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/newsletter/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Can ChatGPT dethrone Gemini? Is Tim Cook capable of leading Apple into the next wave of AI? As 2025 winds down, journalist and podcast host Kara Swisher joins Rapid Response to cut through the noise and decode what’s really happening across OpenAI, Meta, Google, and more. Swisher also sizes up the state of Disney, Netflix, and the escalating bidding war for Warner Bros. Discovery. And in classic Swisher fashion, she doesn’t hold back — weighing in on Elon Musk’s eye-popping potential pay package, Mark Zuckerberg’s costly misfires at Meta, and what the future of AI means for human health and cognition.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.