257 épisodes
- In this episode of Denatured, you’ll hear from Diana Saraceni, founder and managing partner at Panakès Partners and Fabrizio Calisti, medical director at Angelini Ventures. We explore how Italy’s life sciences ecosystem has evolved over the last decade—from stronger tech transfer and growing venture capital to the gaps that still keep it from matching the UK, Germany or France in company creation and scale.
Host
Jennifer C. Smith-Parker, Director of Insights, BioSpace
Guests
Diana Saraceni, Founder and Managing Partner, Panakès Partners
Fabrizio Calisti, Medical Director, Angelini Ventures
Disclaimer: The views expressed in this discussion by guests are their own and do not represent those of their organizations. Replimune finally wins approval, Q2 earnings wrap up, psychedelics stay in spotlight
12/08/2026 | 19 minAfter two rejections, Replimune has made it across the regulatory finish line with its twice-rejected therapy for advanced melanoma. Meanwhile, the last of the major pharmas, including Eli Lilly and Novo Nordisk, reported second quarter earnings, and psychedelics made headlines once again.Rumors of biggest pharma merger ever drop amid Q2 earnings, contentious FDA adcomms
11/08/2026 | 23 minThe industry has been abuzz since the weekend when talks of a potential mega-merger between Bristol Myers Squibb and AstraZeneca were reported. Meanwhile, Pfizer, Merck and others release second quarter earnings, with some disclosing pipeline discontinuations and cost-cutting measures. Finally, all eyes turn to the FDA in the wake of heated advisory committee meetings for Capricor Therapeutics and Replimune.- In this episode of Denatured, you’ll hear from Hans Eriksson, chief medical officer at FundaMental Pharma and Steve Levine, chief patient officer at Compass Pathways. We explore why treatment-resistant depression remains so difficult to address, and how new approaches—from rapid-acting antidepressants to psychedelic therapy—may reshape the treatment paradigm.
Host
Jennifer C. Smith-Parker, Director of Insights, BioSpace
Guests
Hans Eriksson, Chief Medical Officer, FundaMental Pharma
Steve Levine, Chief Patient Officer, Compass Pathways
Disclaimer: The views expressed in this discussion by guests are their own and do not represent those of their organizations. Rumors of biggest pharma merger ever drop amid Q2 earnings, contentious FDA adcomms
05/08/2026 | 24 minThe industry has been abuzz since the weekend when talks of a potential mega-merger between Bristol Myers Squibb and AstraZeneca were reported. Meanwhile, Pfizer, Merck and others release second quarter earnings, with some disclosing pipeline discontinuations and cost-cutting measures. Finally, all eyes turn to the FDA in the wake of heated advisory committee meetings for Capricor Therapeutics and Replimune.
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Unravel the business of science with BioSpace. We dive into biopharma's top stories and biggest challenges, whether it’s layoffs, pipeline shake-ups, acquisitions, new FDA approvals or how to regulate AI in drug development.
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