Neuroscience Perspectives

Revisit the fascinating conversation with best-selling author and neuroscientist Lisa Genova, PhD. Her groundbreaking novel, Still Alice, coupled powerful storytelling with the reality of Alzheimer's disease. It launched Lisa Genova into the spotlight and Hollywood, but most importantly, it deepened the public’s understanding of the neurological condition. Lisa Genova continues to bridge science and storytelling, writing books about left neglect, Huntington’s, ALS, autism, and bipolar disorder. In doing so, she inspires empathy for those affected and reshapes how these diseases are perceived beyond the lab and clinic.
Dr. Genova was a headline speaker at the University of Rochester's Meliora Weekend: https://www.rochester.edu/melioraweekend/meliora-2025-announcement/#lisa
#neuroscience #BrainHealth #LisaGenova
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🧠Experts in this Episode:
Lisa Genova, PhD: https://www.lisagenova.com/
John Foxe, PhD: https://www.urmc.rochester.edu/people/112360965-john-j-foxe

Anne Hart, PhD, professor and Chair of Neuroscience at Brown University, uses C elegans to study genetics, disease, and sleep. In this episode of Neuroscience Perspectives, she tells Dr. John Foxe about the bold move she made early in her career and how it paid off. She also shares the importance of using these simple animal models to ask complex questions.

Dr. Marlene Cohen, professor of Neurobiology at the University of Chicago's Neuroscience Institute, discusses how selective attention helps us pick out what is important in the world around us. Our eyes are constantly bombarded with information, which then enters the brain for processing. This highlights the intricate work of neuroscience in understanding brain function and how we perceive our environment. She is recognized for using multielectrode array recordings to show that a specific pattern of brain activity is reduced when the brain prioritizes information, and that the same mechanism is used when we learn. Today, her research investigates how neural activity gives rise to behavior, particularly in the context of visual attention, and she has also moved into translational work. #neuroscience #cognitive science #brainscience #selectiveattention #optic
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🧠Experts in this Episode:
Marlene Cohen, PhD: https://neurobiology.uchicago.edu/faculty/marlene-cohen
John Foxe, PhD: https://www.urmc.rochester.edu/people/112360965-john-j-foxe
🧠Labs Mentioned:
Marlene Cohen Lab: http://www.cohenlab.com/
Frederick J. and Marion A. Schindler Cognitive Neurophysiology Lab: https://urmc.info/1RG

What is Rett syndrome—and how close are we to effective treatments? In this episode of Neuroscience Perspectives, Dr. John Foxe, director of the Del Monte Institute for Neuroscience at University of Rochester Medicine, sits down with Dr. Jeffrey Neul, a leading expert in pediatric neurology and neurodevelopmental disorders, to explore the latest breakthroughs in Rett syndrome research, clinical trials, and biomarker development. Rett syndrome is a rare genetic neurological disorder that primarily affects girls and is often caused by mutations in the MECP2 gene. Dr. Neul shares how advances in neurogenetics and translational neuroscience are transforming how researchers understand and treat this complex condition. #RettSyndrome #Neuroscience #RareDisease #PediatricNeurology #BrainResearch #Neurodevelopment #ClinicalTrials #MedicalResearch #SciencePodcast #Podcast
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🧠Experts in this Episode:
Jeffrey Neul, MD, PhD: https://vkc.vumc.org/people/neul-jeffrey
John Foxe, PhD: https://www.urmc.rochester.edu/people/112360965-john-j-foxe
🧠Labs Mentioned:
Neul Lab: http://neullab.com/index.html
Frederick J. and Marion A. Schindler Cognitive Neurophysiology Lab: https://urmc.info/1RG

What the hippocampus tells us about exercise, learning, and memory. How organoids are being used in neurodevelopmental research. And the future of medicine and stem cell therapy. In this episode, Dr. Xinyu Zhao, Distinguished Professor of Neuroscience at the University of Wisconsin–Madison, and investigator at the Waisman Center, joins John Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester. Dr. Zhao is internationally recognized for groundbreaking research on the molecular mechanisms that regulate neural stem cells, adult neurogenesis, and brain development, including how disruptions in these processes contribute to neurodevelopmental disorders like autism, fragile X syndrome, and Rett syndrome. Dr. Zhao was a keynote speaker at the 2025 Golisano Intellectual and Developmental Disabilities Institute and Del Monte Institute for Neuroscience Symposium.
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🧠Experts in this Episode:
Xinyu Zhao, PhD: https://neuro.wisc.edu/staff/zhao-xinyu/
John Foxe, PhD: https://www.urmc.rochester.edu/people/112360965-john-j-foxe
🧠Labs Mentioned:
Zhao Lab: https://zhao-lab.com/
Frederick J. and Marion A. Schindler Cognitive Neurophysiology Lab: https://urmc.info/1RG