Neuroscientists Talk Shop

On April 23, 2026 I met with Drs. Vanesa Nieto Estévez and Parul Varma to talk about brain organoids made from cells derived from patients with genetic childhood epilepsy. Vanesa and Parul explained how these patient-derived tissue cultures are used to isolate the defects in brain development that underly the brain disorder, and to suggest and test potential treatments.
Guests:
Vanesa Nieto Estévez and Parul Varma, Assistant Professors of Research, Department of Neuroscience, Developmental and Regenerative Biology, UT San Antonio
Host:
Charles Wilson, Department of Neuroscience, Developmental and Regenerative Biology, UT San Antonio
Thanks to James Tepper for original music

On April 16, 2026, we met with Dr. Robert Froemke of New York University to discuss his work on parenting and co-parenting in mice. We covered a wide range of topics including his video approach to discovery in behavioral experiments and the role of oxytocin in parental behavior.

Guest:
Robert Froemke, Professor, Department of Otolaryngology and Department of Neuroscience at at New York University Langone Health.
Participating:
Alfonso Apicella, Department of Neuroscience, Developmental and Regenerative Biology, UT San Antonio
Alice Bertero, Department of Neuroscience, Developmental and Regenerative Biology, UT San Antonio
Jon Moler, Department of Neuroscience, Developmental and Regenerative Biology, UT San Antonio
Host:
Charles Wilson, Department of Neuroscience, Developmental and Regenerative Biology, UT San Antonio

On April 9, 2026 I spoke with Dr. Marcelo Marucho, on the electrical properties of actin filaments and microtubules, ubiquitous components of the cytoskeleton of nearly all cells. He explained how the surface charge of these proteins creates a thin charged layer in the adjacent cytoplasm in which electrical signals may be generated and conducted. In the case of microtubules, the interaction between external and luminal surfaces can produce oscillations. We discussed some of the possible functions of these electrical signals in the brain.
Guest:
Marcelo Marucho, Professor, Department of Physics and Astronomy, UTSA
Host:
Charles Wilson, Department of Neuroscience, Developmental and Regenerative Biology, UTSA

On April 2, 2026 we met with Dr. Daniel Llano to discuss the organization of the largest subcortical auditory brain structure, the inferior colliculus. He told us about the three major subnuclei within the inferior colliculus, their synaptic connections with other auditory and somatosensory structures, and the problems encountered as we try to identify the cell types and local connectivity within the nucleus.
Guest: Daniel A Llano, Department of Molecular and Integrative Physiology University of Illinois Urbana-Champaign
Participating: Marina Silveira, Department of Neuroscience, Developmental and Regenerative Biology, UT San Antonio
Host: Charles Wilson, Department of Neuroscience, Developmental and Regenerative Biology, UT San Antonio
Thanks to James Tepper for original music

On March 26, 2026, we held our annual UTSA Neuroscience Symposium entitled "From Place Cells to Cognition", featuring 5 speakers presenting original research on the cognitive functions of hippocampal place cells. They discussed the firing patterns of place cells during exploration of cognitive maps, anticipating future movements, recall of previously visited locations, and imagining the movement of objects in the environment. After the symposium, I met with the speakers to review some of the themes that emerged throughout the day.
Speakers:
Francesco Savelli, Assistant Professor, Department of Neuroscience, Developmental and Regenerative Biology, UTSA
Annabelle Singer, Associate Professor, Department of Biomedical Engineering, Georgia Institute of Technology and Emory University
Albert Lee, Associate Professor, Department of Neurology and Howard Hughes Medical Institute, Harvard University
Jill Leutgeb, Professor, Department of Neurobiology, University of California San Diego
Kamran Diba, Associate Professor, Department of Anesthesiology, University of Michigan
Host:
Charles Wilson, Department of Neuroscience, Developmental and Regenerative Biology, UTSA
Thanks to James Tepper for original music